Wegovy Interactions: Which Medications Can It Interact With?

Wegovy is a helpful weight loss medication, but it’s important to know how it may interact with other medications or supplements. Being aware of these interactions helps ensure Wegovy is used safely and minimises the risk of serious side effects. Here’s a guide on what to watch for and how to talk to a healthcare provider about your medications when considering Wegovy.

Key Takeaways

Wegovy May Interact with Prescriptions

Wegovy can affect other medications, especially diabetes drugs and blood pressure medications. If you're on insulin, your dose may need adjusting to prevent low blood sugar. Always let your healthcare provider know about all prescription medications you're taking to ensure the safe use of Wegovy.

OTC and Supplements May Also Interact

Certain over-the-counter (OTC) products and supplements, such as fat-soluble vitamins (A, D, E, K) and herbal products like St. John’s Wort, may interact with Wegovy. Discuss any supplements with a healthcare provider to prevent absorption issues or side effects.

Precautions and Symptom Monitoring are Key

To use Wegovy safely, keep your healthcare provider informed of any medication changes and watch for symptoms like unexpected low blood sugar or digestive issues. By sharing all your medications and supplements, you can minimise risks and make your Wegovy treatment as effective as possible.

Can Wegovy interact with other prescriptions?

Yes, Wegovy can interact with certain medications [1]. Some common interactions include:

Diabetes medications:

Wegovy can lower blood sugar, so if you take insulin or other diabetes medications you may need to adjust your doses to avoid low blood sugar.

Blood pressure medications:

Weight loss from Wegovy may also lower blood pressure. If you’re already on blood pressure medication, your healthcare provider may monitor and adjust your dosage.

Other GLP-1 medications:

Wegovy should not be combined with other GLP-1 receptor agonists (like Ozempic), as this can increase the risk of side effects.

Always inform your healthcare provider of all medications you take, as they can help adjust doses if needed.

Can Wegovy interact with over-the-counter medications or supplements?

Yes, certain over-the-counter (OTC) medications or supplements may interact with Wegovy:

Vitamin supplements:

Some vitamins, especially fat-soluble ones like A, D, E, and K, may be absorbed differently as Wegovy changes digestion. Speak to a healthcare provider about any supplements you use.

Herbal supplements:

Some herbal supplements, like St. John’s Wort, can interact with medications, so it’s best to check before combining these with Wegovy.

It’s always safest to discuss any supplements with a healthcare provider to avoid unwanted interactions.

What precautions should you take with other medications when using Wegovy?

To use Wegovy safely, follow these precautions:

Share your medication list:

Tell your healthcare provider about all prescription and OTC medications, vitamins, and supplements you use.

Monitor for changes:

If you start or stop any medication, let your healthcare provider know. They can help watch for any changes or side effects.

Being open with your healthcare provider about all of the current medications that you are taking ensures that your Wegovy treatment is as safe and effective as possible.

What symptoms should you watch for?

If Wegovy interacts with other medications, you might notice side effects like:

• Unexpected low blood sugar (feeling shaky, sweaty, or lightheaded).

• Unusual digestive issues, especially if taking vitamins or herbal supplements.

If any symptoms seem unusual or severe, contact your healthcare provider right away.

Wegovy can interact with some prescription medications, OTC medications and supplements, so it’s essential to share a full list of what you’re taking with your healthcare provider. By working together, you can safely manage your weight with Wegovy while minimising the risk of unwanted interactions.

Understanding the Benefits and Risks of Wegovy for Weight Loss

Considering Wegovy for weight loss? Our guide explains the main benefits and risks to help you make an informed choice. Learn how Wegovy can support weight management, the common side effects to expect, serious warnings to keep in mind, and how it compares to lifestyle changes alone. Whether you’re curious about medication interactions or simply want to know if Wegovy is right for you, this guide covers all the basics.

Medically Reviewed by:
Dr. Alexis Missick MBChB. MRCGP
GMC reference no: 7151419
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References

[1] Wegovy Interactions Checker - Drugs.com