Istin (Amlodipine)

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Istin is used for the treatment of high blood pressure or a certain type of chest pain called angina. Istin contains the active ingredient amlodipine, which belongs to the group of medicines called calcium antagonists.

  • Calcium channel blocker medication
  • Widens blood vessels
  • Lowers blood pressure
  • Genuine medication
  • All drugs sourced in the UK
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A Doctor's Overview

Dr Shane Charles (MBBS, MRCS, PgDip SEM) - GMC Number 8085739

GP and surgeon, Dr Shane Charles (MBBS, MRCS, PgDip SEM) provides a simple explanation of the medication below:

'Istin is a medication used to treat high blood pressure that works by blocking calcium channels. '.

If you think this is a treatment that can help you, start an online consultation now for a registered prescriber to review. If treatment is deemed suitable, they can prescribe it, and we can deliver it to you from the comfort of your own home with a range of convenient delivery and payment options for you to choose from. If you have any questions about a medication, you should always consult your doctor with any questions prior to starting treatment, to ensure that it is safe and suitable for you.

Buying Istin Online in the UK

You can order Istin (a prescription medicine for high blood pressure and angina) safely online at UK Meds.

Before it’s supplied, you’ll need to complete a free online consultation with a registered independent prescriber. This is to make sure Istin is safe and suitable for your health needs.

Once approved, your medication will be delivered straight to your door.

Istin - Key Information

Istin is a prescription medicine used to treat high blood pressure (hypertension) and angina (a type of chest pain).

Amlodipine

It contains the active ingredient amlodipine, which is part of a group of medicines called calcium channel blockers. These work by relaxing the blood vessels, making it easier for blood to flow.

How Does Istin Work?

  • For high blood pressure, Istin helps by relaxing and widening the blood vessels, which lowers pressure and helps your heart work more easily.

  • For angina, Istin increases blood flow to the heart, which helps prevent chest pain.

    Note: It’s not for quick relief of sudden chest pain – it’s used regularly to help prevent it.

Benefits of Taking Istin

  • Helps lower blood pressure, reducing the risk of heart attacks and strokes.

  • Helps prevent chest pain linked to angina.

  • Makes it easier for your heart to do its job, helping you feel more comfortable in everyday life.

Always take Istin exactly as prescribed by your doctor, and read the patient leaflet for guidance.

Istin Reviews

Read first hand what other UK Meds customers think about Istin and it's impact on patients lives on our customer reviews above. For further context there are also a large selection of Istin reviews describing what people think about their experiences with the medication available at Drugs.com and Web MD.

It is important to note that people may have different experiences when they use Istin. If someone states that their medication did not work as they had hoped, it does not mean that it will not work for you. If you believe that it is the right medication for you then the best thing to do is to consult your doctor or healthcare professional, and judge the medication based on your own experiences if they recommend it as a treatment. Before starting a medication you should always consult with your healthcare provider first to ensure that it is safe and suitable for your individual needs.

For more information on the prescription medication patients should refer to the Istin patient information leaflet.

Usage Advice

How to Take Istin (Amlodipine)

If you've been prescribed Istin (which contains amlodipine) for high blood pressure or angina, here’s how to take it safely and effectively:

  • Follow your doctor’s instructions exactly. If you're unsure, ask your doctor or pharmacist.

  • Take one tablet each day, around the same time. You can take it before or after food.

  • Use water to swallow the tablet. Avoid taking Istin with grapefruit juice, as it can affect how the medicine works.

  • If you forget a dose, just skip it and take the next one as normal. Don’t take two tablets at once to make up for it.

  • Keep taking Istin for as long as your doctor tells you to – don’t stop suddenly, even if you feel better, as your condition may return.

For any questions or if you’re not sure about anything, speak to your doctor or pharmacist.

Dosage

The typical starting dose of Istin (amlodipine) for adults in the UK is 5mg once a day. If needed, your doctor may increase this to a maximum of 10mg daily, depending on how you respond to treatment.

For children aged 6 to 17, the usual starting dose is 2.5mg once a day, with a maximum daily dose of 5mg. Istin 5mg tablets can be split in half to get the 2.5mg dose if required.

Always take the dose exactly as prescribed by your doctor and never adjust it yourself without medical advice.

Side Effects & Precautions

Like all medicines, Istin can cause side effects and may not be suitable for everyone.

Serious Side Effects – Seek Medical Help Immediately

Stop using Istin and contact your doctor straight away if you experience:

  • Sudden wheezing, chest tightness, or shortness of breath

  • Swelling of the face, lips, tongue, or throat

  • Severe skin reactions including rashes, blistering, or peeling

  • Severe stomach or back pain (possible signs of pancreatitis)

  • Heart attack symptoms or irregular heartbeat

Common Side Effects of Istin

  • Swelling of the ankles or feet (oedema)

  • Headache, dizziness, or feeling sleepy

  • Flushing (warm or red skin)

  • Stomach pain, nausea, or indigestion

  • Tiredness or general weakness

  • Changes in bowel habits (constipation or diarrhoea)

  • Muscle cramps

Uncommon Side Effects

  • Tingling or numbness in hands and feet

  • Mood changes, anxiety, or trouble sleeping

  • Ringing in the ears

  • Dry mouth or vomiting

  • Rash, itching, increased sweating, or skin discolouration

  • Back pain, joint pain, or weight changes

  • Erectile dysfunction or breast swelling in men

Very rare side effects include confusion or fainting.

Warnings and Precautions

Do not take Istin if:

  • You are allergic to amlodipine or any other ingredient in the medicine

  • You have very low blood pressure

  • You have a heart valve condition or heart failure following a heart attack

Speak to your doctor before taking Istin if you:

  • Have heart failure or have recently had a heart attack

  • Have liver disease

  • Have extremely high blood pressure

  • Are elderly and may require dose adjustments

Additional Precautions

  • Do not take Istin with grapefruit or grapefruit juice as this can increase the effect of the medicine and lower your blood pressure too much

  • Istin may cause dizziness or tiredness – avoid driving or using machinery until you know how it affects you

  • Let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding

Children and Adolescents

Istin should only be used to treat high blood pressure in children aged 6 to 17. It is not recommended for children under 6.

Drug Interactions

Although Istin does not commonly interact with many medicines, always inform your doctor about any other medications, including herbal supplements or over-the-counter treatments.

Important: Always take Istin as directed by your doctor. Read the patient information leaflet in full and contact your GP or pharmacist if you have any concerns.

Learn more with UK Meds support resources for Istin:

Read our helpful blogs to gain a better understanding of managing your blood pressure:

Author

Content author

Scott Weaver

Medical Content Writer • Bachelor of Arts Degree

Scott is an experienced, skilled medical content writer dedicated to creating helpful and accessible medical content for UK Meds.

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